Member Spotlight: Hongmei Wang, PhD

Hongmei Wang, PhD
Institute of Zoology, Chinese Academy of Sciences, China

Hometown
Inner Mongolia

Current Residence
Beijing

Graduate Degree
Ph.D.

Postdoc Work
Postdoctoral training (2003-2005) at the Ottawa Health Research Institute, University of Ottawa.  

Current Position
Researcher and Professor

ISSCR Participation
Anne McLaren Memorial Lecture Speaker at the ISSCR 2025 Annual Meeting

• What is the current focus of your research?

  Deciphering the mechanisms of early embryonic and placental development, alongside the exploration of various culture systems that facilitate extra-uterine embryogenesis.  

• How would you explain the significance of this work to a lay audience?

  The development and functionality of the placenta are vital for sustaining a healthy pregnancy. Aberrations in placental development can lead to pregnancy-related complications and diseases. Our research delves into the mechanisms underlying in vivo embryonic and placental development, providing insights into maternal-fetal adaptive mechanisms during gestation. This understanding could pave the way for unraveling developmental disorders and maternal pregnancy complications, ultimately enhancing reproductive health and quality of life, thereby benefiting human propagation.  

• What do you find most rewarding about your work?

  The most rewarding aspect of my work is the impact our research has on understanding the complexities of early mammalian embryonic and placental development. Witnessing how our findings can translate into clinic applications, ultimately improving health outcomes for mothers and infants, is incredibly fulfilling. Additionally, mentoring students and witnessing their growth as they contribute to this vital field adds another layer of satisfaction, as I realize that our collective efforts are shaping the future of the field. 

• What is the most exciting aspect of your work?

  The most exciting aspect of my work lies in the constant pursuit of knowledge and innovation. I am particularly passionate about mentoring the next generation of scientists. Witnessing my students develop their own ideas and make significant contributions to the field is incredibly fulfilling. Their enthusiasm and fresh perspectives often inspire me and enrich my own research as well. 

• What led you to become a scientist and to stem cell research?

  My path to becoming a scientist was shaped by a deep seated curiosity about the complexities of human early embryonic development and a desire to address pressing health challenges, particularly those related to pregnancy and congenital disorders. The transformative potential of stem cell research captivated me, as it holds the promise to unravel the intricacies of development and regeneration.  

• What guidance would you share in talking with trainees interested in pursuing your area of research?

  I would advise aspiring scientists to cultivate an unwavering curiosity and enthusiasm for research. Embrace a mindset of critical inquiry, don't just accept existing theories, but seek to question and expand upon them. Collaboration is also key, engaging with colleagues from diverse backgrounds can enrich your perspective and spark innovative ideas.  

• Do you have any mentors or individuals who have inspired you in your stem cell work?

  Qi Zhou from our Institute and Jay Cross from U Calgary 

• How do you spend your free time?

  In my leisure time, I enjoy running, reflecting, engaging in physical activities, cooking, and keeping abreast of the latest scientific advancements.  

• What do you most value about your membership with the ISSCR?

  I greatly value the opportunity to engage with peers, share our work, and inspire the enthusiasm of emerging young scientists.