ISSCR News


New Podcast Episode. A Look Into the Future of Stem Cell Reports: A Conversation with Janet Rossant
Announcements Megan Koch Announcements Megan Koch

New Podcast Episode. A Look Into the Future of Stem Cell Reports: A Conversation with Janet Rossant

In this special edition of the podcast, we will talk with the new Editor-in-Chief Janet Rossant and hear about her vision for the journal, its promising future, and what she sees as some of the exciting prospects over the horizon for stem cell research. We will also talk with Yvonne Fisher, the journal’s Managing Editor, and Jack Mosher of the ISSCR, about the evolution of the journal and its role in the Society.

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Global Survey Seeks to Evaluate Feedback Practices to Create a More Inclusive Environment for Researchers
Announcements Kym Kilbourne Announcements Kym Kilbourne

Global Survey Seeks to Evaluate Feedback Practices to Create a More Inclusive Environment for Researchers

The ISSCR is working with researchers out of the University of Greenwich, UK on a project that aligns with the Society’s strategic priorities to foster inclusivity, collaboration, and excellence within the research community. This initiative seeks to enhance feedback practices across disciplines and regions, creating a more inclusive environment that particularly benefits early-career and marginalized researchers.

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New Podcast Episode. SeqVerify: A New Easily Accessible Tool for Comprehensive Cell Line Quality Assessment
Announcements Megan Koch Announcements Megan Koch

New Podcast Episode. SeqVerify: A New Easily Accessible Tool for Comprehensive Cell Line Quality Assessment

During the last decade, advances in genome editing and pluripotent stem cell (PSC) culture have let researchers generate edited PSC lines to study a wide variety of biological questions. However, abnormalities in cell lines such as aneuploidy, mutations, on-target and off-target editing errors, and microbial contamination can arise during PSC culture or due to undesired editing outcomes. To ensure valid experimental results and the safety of PSC-derived therapeutics, it is important to detect these abnormalities and choose PSC lines without them. Existing quality control methods typically focus on detecting one type of abnormality. Whole genome sequencing is an all-in-one detection method for any abnormality involving changes to DNA sequences but until now it has required considerable computational expertise. Today’s guests will discuss a new computational tool, SeqVerify, that analyzes short-read WGS data for quality control of wild-type or edited PSCs. The platform provides an end-to-end analysis framework that can be a valuable quality control method for researchers working with PSCs, and more broadly, for cell line quality control in general.

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