ISSCR News
Stem Cell-Derived “Spinal Cord-Like” Microtissues Afford Personalized Drug Screening
Amyotrophic lateral sclerosis (ALS) is a fast-progressing neurodegenerative disease with an average survival time of three years and no effective treatments. In ALS, motor neurons in the spinal cord, which are required for muscle contractions, die off, leading to progressive muscle paralysis. The molecular causes of ALS are poorly understood, but neuroinflammation, a process of excessive inflammation fueled by immune cells in the spinal cord, is thought to contribute to motor neuron death in ALS. Reducing neuroinflammation may be a tractable way to treat ALS.
ISSCR Working Group Recommends Enhanced Oversight of Stem Cell-Based Embryo Models in Response to Rapid Technological Advances
The International Society for Stem Cell Research (ISSCR) Embryo Models Working Group has released updated recommendations for the oversight and regulation of stem cell-based embryo models (SCBEM), aiming to address rapid advancements and ensure responsible scientific progress. The proposed recommendations are detailed in a new paper published today in Stem Cell Reports.
SCBEMs are three dimensional structures that replicate key aspects of early embryonic development, offering unprecedented potential to enhance our understanding of human developmental biology and reproductive science.
Message from the President | Year in Review: 2024-2025
As I reflect on this past year as ISSCR President, I feel gratitude for what I have learned and the outlook it has given me on the Society and on the field it represents. I will share a few reflections below.
As I began in my role, I realized that I had only a superficial understanding of the work of more than 200 volunteers and ISSCR team members. With Director of Media and Strategic Communications Kym Kilbourne, I have embarked on monthly interviews and email correspondence with colleagues in leadership roles to learn about the work of the ISSCR committees, task forces, and working groups. It has been humbling to listen to them and to experience the passion and commitment each of them brings to our Society. Their work spans large subfields of regenerative biology and medicine allowing us to form public and regulatory policy priorities, educate ourselves and others, participate in manufacturing innovations, and wrestle with important ethical questions, to name just a few. It was a privilege to report on their work monthly in my president’s messages.
Member Spotlight: Robert Zweigerdt, PhD
Being ISSCR member for 25 years is like being part of the leading global network in stem cell science, which has turned into an “dynamic, growing family” over the years.
The ISSCR Launches First Online Global Continuing Education Course on Stem Cell Medicine
The International Society for Stem Cell Research (ISSCR) announces the launch of a new online continuing education course, Stem Cell Medicine: From Scientific Research to Patient Care. The comprehensive course comes at a pivotal moment, addressing the growing demand for evidence-based, expert-led education amid the proliferation of unproven and potentially harmful stem cell interventions that threaten patient safety around the world. The activity, jointly provided by Harvard Medical School and the ISSCR, is open access, available on demand, and offered at no cost to clinicians, nurses, medical students, scientists, and the public. It is also available in five languages.
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