In a paper recently published in Stem Cell Reports, researchers followed-up with a screen of 464 drugs and identified a small group of about 20 that reduced C4 secretion from astrocytes. These drugs were effective both in healthy astrocytes & in astrocytes made from Schizophrenia patients’ stem cells.

Sensory neurons of the peripheral nervous system, which sense touch, temperature, and pain, can be permanently lost during infections, trauma, in response to certain medications, and in diabetic patients with peripheral neuropathy. Current treatments reduce symptoms but cannot bring back lost sensory neurons, which are thought to have a very limited ability to regenerate after injury or disease A recent study in Stem Cell Reports shows that there are stem cells in the sensory nervous system of mice with the potential to regenerate lost neurons and glia.